laboratory study indicates that some mangosteen extracts and constituents may cause cardiovascular, central nervous system, and musculoskeletal adverse effects. Based on this preliminary study, use cautiously in patients with cardiovascular disease, clotting disorders, or using anticoagulation medicine. Also, use cautiously in patients using chemotherapeutic agents, as mangosteen may interact with chemotherapeutic agents (i.e., anthracyclines, platinum compounds, and alkylating agents) whose mechanism of action involves oxidation.
Pregnancy and Breastfeeding
Mangosteen is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.
Adults (18 years and older):
There is no proven safe or effective dose for mangosteen.
Children (younger than 18 years):
There is no proven safe or effective dose for mangosteen, and use in children is not recommended.
Note: The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
